Version: v1.0 Release Date: 2023.12.25 Last Update Date: 2023.12.25
Introduction: The purpose of Hi-C is to understand the three-dimensional conformation of nuclear chromatin, obtain chromatin sequencing fragments that are very close in spatial position or interact with each other in the cell nucleus, so as to better study the interaction within or between chromatin, and the regulation of gene regulatory elements on a genome-wide scale. If you have a hic format file, you need to use the hicConvertFormat of the HiCexplorer software to convert the .hic/ hicpro matrix file into the ginteractions format before using this function, and then convert it into a three-column format file of txt or csv. You can also use the Straw tool.